Abstracto

A novel diagnostic tool for identifying patients with inflammatory and/or virally induced cardiomyopathies is microRNA profiling.

Peter Abbey

For the purpose of determining whether an inflammatory or viral process is to blame for undiagnosed heart failure, microRNAs (miRNAs) could be used as potential biomarkers. Prognostic miRNAs in the serum of patients with inflammatory heart diseases discovered through end myocardial biopsies were the focus of this study The identification of patients with intramyocardial inflammation and/or viral persistence solely from a single serum sample, independent of prescribed therapy and the time of onset of symptoms, is made possible for the first time by this miRNA profile, which offers a novel non-invasive diagnostic perspective. It makes it possible to identify patients who are suitable for myocardial biopsy early on, allowing for a precise diagnosis and subsequent prescription of specific treatment based on causal aetiology